Research Centre PandemiX Center
PandemiX – Center for Interdisciplinary Study of Pandemic Signatures – is a Center of Excellence funded by The Danish National Research Foundation (DNRF). We are an interdisciplinary research center that studies pandemics in all their inherent complexity. The Center’s overall research objective is to investigate the signature features of COVID-19 and pandemics of the past, to better understand both and to better prepare for future pandemics.
Pandemics have afflicted humanity throughout recorded history. When new diseases emerged, acquired immunity in the human population and evolutionary changes in the pathogens brought the ensuing pandemics to an end. As scientific tools to understand and reduce the harms from pandemics have improved, the study of pandemics has expanded from history and demography to also encompass quantitative research in fields such as population biology and applied mathematics.
PandemiX unites studies of the historical and contemporary record of experienced pandemics in a radically interdisciplinary environment. By taking such a wide view, we strive to make breakthroughs not hitherto possible or attempted, ranging from a profound understanding of how to control transmission in the short run, to how best to secure robust population immunity in decades to come. The PandemiX Center will give rise to a new field, pandemiology, home to a growing cadre of interdisciplinary researchers ready to address the inevitable next pandemic.
Roskilde University (RUC) Department of Science and Environment (DSE), is the host institution of the PandemiX Center. Furthermore, PandemiX has an office suite at Statens Serum Institute (SSI).

Interdisciplinary research field with World-class data
The PandemiX Center will focus on building a strong quantitative base with researchers in areas such as mathematical modelling, historical epidemiology, bioinformatics and clinical research. Denmark is an ideal place to establish such a centre because we have both historical health data and contemporary register data that allows us to study and understand both historical and contemporary pandemics in far greater depth than in most other countries.
About PandemiX

Center staff
PandemiX brings together in one organization a diverse team of experts with four core competencies: mathematical modelling of infectious diseases, historical epidemiology, clinical research, and bioinformatics.

Mission and programmes
The goal of PandemiX is to build a comprehensive understanding of the forces that shape pandemic trajectories from origin to endgame, as we describe and quantify the signature features of pandemics present and past.
We have organized our research plan into six intertwined research programmes. Together, these programmes will address all aspects of the entire pandemic cycle. All six programmes require two or more of our listed core competencies. The program teams will collaborate extensively.

Follow PandemiX Center on X (Twitter)
On X (the former Twitter), you can read our comments on and answers to the many questions that are about COVID-19 and the Corona pandemic.
You can also follow the research at the Center of Excellence. The profile is edited by the researchers at PandemiX Center.

Opening of a new Center of Excellence: Will make us smarter about future pandemics
There were speeches, jazz music and high spirits when Roskilde University's new Center of Excellence PandemiX opened last Friday. Professor Lone Simonsen will head the new center, which the Danish National Research Foundation has invested DKK 47 million in.

In Nature Communications: The counterintuitive implications of superspreading diseases
Superspreading is known to have played an important role in the transmission dynamics of SARS-CoV-2. In this Comment in Nature Communications, PandemiX researchers discuss how knowledge of the extent and cause of superspreading is important for designing appropriate control measures for emerging infectious diseases.

Reseach projects
The PandemiX Center participates in a number of research projects, which are both internally and externally funded, just as the center's researchers participate in projects in collaboration with other research institutions in Denmark and abroad.
Publications
A Candidate DNA Vaccine Encoding the Native SARS-CoV-2 Spike Protein Induces Anti-Subdomain 1 Antibodies
Frische, A., Gunalan, V., Krogfelt, K. A., Fomsgaard, A. & Lassaunière, R., Sept 2023, In: Vaccines. 11, 9, 1451.Research output: Contribution to journal › Journal article › Research › peer-review
A Cross-Sectional Study of SARS-CoV-2 Antibodies and Risk Factors for Seropositivity in Staff in Day Care Facilities and Preschools in Denmark
Fogh, K., R. R. Eriksen, A., G. Larsen, T., B. Hasselbalch, R., Bundgaard, H., F. S. S. Scharff, B., D. Nielsen, S., S. Jørgensen, C., Erikstrup, C., Østergaard, L., Ellermann-Eriksen, S., Andersen, B., Nielsen, H., S. Johansen, I., Wiese, L., Hindhede, L., Mikkelsen, S., Sækmose, S. G., Aagaard, B., K. Holm, D., & 16 others , 2023, In: Microbiology Spectrum. 11, 1, p. e0417422Research output: Contribution to journal › Journal article › Research › peer-review
Aggregative adherence fimbriae form compact structures as seen by SAXS
Jønsson, R., Björling, A., Midtgaard, S. R., Jensen, G. V., Skar-Gislinge, N., Arleth, L., Matthews, S., Krogfelt, K. A. & Jenssen, H., 2 Oct 2023, In: Scientific Reports. 13, 1, 16516.Research output: Contribution to journal › Journal article › Research › peer-review
Activities
5th Conference of the European Society of Historical Demography
Maarten van Wijhe (Participant)
30 Aug 2023 → 2 Sept 2023Activity: Participating in or organising an event › Organisation and participation in conference
Pandemics of the Past, Present and Future: Reflections of an epidemiologist
Lone Simonsen (Speaker)
22 Mar 2023Activity: Talk or presentation › Lecture and oral contribution
SNSF Corona Research Conference
Lone Simonsen (Participant)
22 Mar 2023Activity: Participating in or organising an event › Organisation and participation in conference
Press-media
Host, host! Er alle mennesker syge? Hvorfor lige nu – og skal vi være bekymrede?
07/12/2023
1 item of Media coverage
Press/Media: Press / Media
Var det klogt at lukke skoler og give ordre om mundbind?
01/12/2023
1 item of Media coverage
Press/Media: Press / Media

More about Roskilde University
The research center is based at Department of Science and Environment
Participating research units: Mathematics and Physics (IMFUFA), Molecular and Medical Biology
PhD Programme: Doctoral School of Science and Environment
Relevant degree programmes: Matematical Bioscience // Molecular Health Science // International Bachelor in Natural Sciences
Research at Roskilde University

More about the centre
Find additional information about the PandemiX Center
The research centre at the Roskilde University Research Portal
Meet us on Twitter

Contact
Lone Simonsen
Director, head of research centre, professor
Phone +45 2342 9503
lonesimo@ruc.dk
Johanne Greibe Andersen
Centre coordinator
Phone +45 4674 3980
johannea@ruc.dk