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Chemistry

The Chemistry Research Group conducts research in fundamental and applied chemistry often in close collaboration with biologists and physicists. Common to all activities is an interest in modeling chemical processes often with an experimental approach and testing. The research group covers a broad spectrum of chemical disciplines and works within organic, inorganic, analytical and bioorganic chemistry. Key areas of interest are:

  • Catalysis (hydrolytic enzymes)
  • Energy (solar cell chemistry, electrochemistry)
  • Complex aqueous systems (binding thermodynamics and micellization)
  • Organic synthesis (bioactive compounds, drug delivery systems)
  • Analytical chemistry (chromatography and mass spectrometry methods, sensor development and multivariate analysis)
  • Biophysical and biological chemistry (gelation and hydrogen bonding, protein stability and structure by NMR)

Many research projects are conducted in close collaboration with internal and external academic partners. Furthermore, the Chemistry research group also has long-standing collaborations with major Danish and international private companies.

Kemi facilitet

News

Excerpt from the artwork Chemophilia 1 by Thomas Ruhland

New artwork honors the work of Professor Emeritus Poul Erik Hansen

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On the occasion of Professor Emiritus Poul Erik Hansen's 75th birthday, the Chemistry Research Group has donated the artwork Chemophilia 1 to Roskilde University. The artwork is created by the German artist Thomas Ruhland, who draws on inspiration from his many years of work as a medicinal chemist.
Biljana Mojsoska

Can nanomaterials be used as shields against bacteria and viruses?

| News
Is it possible to create new nanomaterials that can form surfaces capable of recognising and degrading harmful bacteria or viruses? Scientists from Roskilde University are about to investigate this in a new research project that has received DKK 2 million from Villum Experiment.
Picture of scientist using HPLC equipment to separate CBD from other cannabis molecules.

Substance derived from the cannabis plant can combat MRSA

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In new results, scientists from Roskilde University have shown that individual chemical components of cannabis have an effective impact on methicillin-resistant Staphylococcus aureus (MRSA). The results confirm existing research and add crucial new knowledge on how active molecules from the cannabis plant can be applied in combination with a number of traditional antibiotics currently used to treat MRSA in humans. The results could lay the groundwork for the development of new types of medicine that could reduce consumption of conventional antibiotics and curb the growth of antibiotic resistance.

  • Contact

    William Goldring, Associate Professor, goldring@ruc.dk
     

    Reseachers

    Reseachers in Chemistry

  • Based in a new building equipped with modern infra-structure, chemistry researchers in the DSC work with state-of-the-art instrumentation and analytical facilities, such as:

    Mass Spectrometry

    Associate Prof. Torben Lund (tlund@ruc.dk)
    Associate Prof. Biljana Mojsoska (biljana@ruc.dk)
    Rosa Jersie-Christensen, PhD (rrj@ruc.dk)

    LC-MS

    LTQ-XL Thermo Finnigan linear ion-trap mass spectrometer with a HESII electro spray ion source, coupled to a Dionex Ultimate 3000 UHPLC and a diode array detector.
    Instrument use: Analysis of ruthenium dyes, natural products, intact proteins, peptides, organic reaction mixtures.

    LTQ-Orbitrap Velos high resolution mass spectrometer coupled to a Dionex Ultimate 3000 nano-HPLC.
    Instrument use: Proteomics and exact mass determinations.

    GC-MS

    Thermo Scientific Trace 1300 GC coupled to a ISQ-7000 EI-MS and a TDC detector. The instrument includes a Triplus RSH autosampler with PTV and head-space injection.
    Instrument use: PCB and gas-molecule detection (H2, CO, CO2…).

    Nuclear Magnetic Resonance (NMR) Spectrometer

    Associate Prof. William Goldring (goldring@ruc.dk)
    Associate Prof. Anders Malmendal (amalm@ruc.dk)
    Operator: Annette Christensen (acis@ruc.dk)

    Bruker Ascend 400 MHz, including auto-sampler and BCU II variable temperature control
    Instrument use: Analysis of synthesis and natural products, biological material, and molecular complexes. Methods include, structure characterization and elucidation using a variety of routine and non-routine one- and two-dimensional experiments.

    Dynamic Light Scattering (DLS)

    Associate Prof. Søren Hvidt (hvidt@ruc.dk)

    Malvern Zetasizer Nano-S
    Instrument use: Analysis of nanoparticles, including materials and biological complexes, for particle size measurement and polydispersity determination.

    Other instruments

    The section is also equipped with a number of other instruments, such as infrared and UV spectrometers, preparative and analytical chromatographic equipment (HPLC, radial LC, size exclusion), rheometers (Bohlin VOR and Haake RS100), calorimeters (ITC and DSC), photochemical lamps (400 and 125 W medium pressure Hg) and reaction vessels, and chemical computation facilities (Gaussian and Macromodel).

Publications

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Activities

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Insights

Biljana Mojsoska
ARTICLE

Can nanomaterials be used as shields against bacteria and viruses?

Is it possible to create new nanomaterials that can form surfaces capable of recognising and degrading harmful bacteria or viruses? Scientists from Roskilde University are about to investigate this in a new research project that has received DKK 2 million from Villum Experiment.

Picture of scientist using HPLC equipment to separate CBD from other cannabis molecules.

Substance derived from the cannabis plant can combat MRSA

In new results, scientists from Roskilde University have shown that individual chemical components of cannabis have an effective impact on methicillin-resistant Staphylococcus aureus (MRSA). The results confirm existing research and add crucial new knowledge on how active molecules from the cannabis plant can be applied in combination with a number of traditional antibiotics currently used to treat MRSA in humans. The results could lay the groundwork for the development of new types of medicine that could reduce consumption of conventional antibiotics and curb the growth of antibiotic resistance.

Biljana Mojsoska
ARTICLE

Breakthrough in the search for a new treatment for multi-drug resistant tuberculosis

Chemist Biljana Mojsoska and molecular biologist Håvard Jenssen from Roskilde University have in collaboration with international research colleagues developed and tested new antimicrobial drugs that can be used as an alternative to antibiotics in the fight against the infectious disease tuberculosis. The mycobacteria that triggers tuberculosis develops resistance to more and more known antibiotics.

Overblik over forskning på RUC

Base at Roskilde University

The research groupis based at Department of Science and Environment

Related research units: FRUSTMI reseach centre // Environmental Dynamics research group // Molecular and Medical Biology reseach group // Mathematics and Physics research group

PhD Programme: Doctoral School of Science and Environment

Uddannelser og fag: Chemistry // Chemical Biology // International Bachelor in Natural Sciences

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More information

Find additional information about Chemistry:

Research group website at Roskilde University Research Portal

Profil

Contact

Research group leader

William Goldring
Associate Professor
Phone +45 4674 2308
goldring@ruc.dk