IMFUFA-seminar: NMR and multivariate analysis in biological and biophysical systems

Anders Malmendal is Associate Professor in Chemistry at Roskilde University. Here he will tell you a bit about the tools he is using in his research, including how NMR can be used to monitor molecular size, structure, and dynamics, and provide examples describing macromolecular oligomerization and metabolic processes.
Onsdag
15
april
Start:kl. 14.00
Slut:kl. 16.00
Sted: Roskilde Universitet, Universitetsvej 1, Bygning 27.1, lokale I (27.1-189)

My most important research tools are nuclear magnetic resonance spectroscopy (NMR), which provides information on almost every atom in a molecule or a mixture of molecules, and multivariate analysis (MVA), which is very useful to make sense of this complex information.

The combination of NMR and MVA is traditionally explored in metabolomics, where MVA is used to identify the underlying biological processes from NMR-snapshots of all the small molecule metabolites in a number of biological samples obtained under different conditions.

For macromolecules one can record NMR spectra as a function of time and use multivariate methods to decipher time-courses of events such as the emergence of new structures and exchange between various species in solution.

Here I will tell you a bit about these tools, including how NMR can be used to monitor molecular size, structure, and dynamics, and provide examples describing macromolecular oligomerization and metabolic processes.

Seminaret foregår på engelsk.

Tilmelding

Alle er velkomne, tilmelding er ikke nødvendig.

Find vej

Find vej til Roskilde Universitet